There are numerous treatment options for premature ejaculation (PE), including prescription and over-the-counter (OTC) drugs. Viagra (sildenafil) and Cialis (tadalafil) are examples of tablets. So, pills to help me last longer in bed.
PE is a form of sexual dysfunction affecting up to 30% of individuals with a penis. It may be a temporary or chronic condition. Some individuals seek medication to alleviate their symptoms, which include ejaculating within one minute of penetration and having trouble regulating or delaying ejaculation during penetration.
While there is no cure for PE, treatment may alleviate symptoms in 30–70%Trusted Source of cases. However, it is essential to note that symptom recurrence is standard and will require additional treatment.
What are the best PE pills?
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Always consult a physician before taking medication to treat PE, as certain medicines may interact with other drugs or preexisting conditions. The most secure choice is to seek advice from a medical professional.
The following prescription and nonprescription pills may assist with PE:
- Particular erectile dysfunction (ED) medications have side effects.
- antidepressant medications
- Analgesics, which are pain-relieving medications
Certain ED medications can also aid in the treatment of PE. The treatment of PE with these is an unapproved use.
They are referred to as phosphodiesterase 5 (PDE5) inhibitors and include:
- Sildenafil (Viagra) is used to treat impotence.
- The brand name for tadalafil is Cialis.
- Levitra’s vardenafil
- The drug avanafil (Stendra)
They function by affecting the enzymes in the penis and lungs to prolong erections and reduce pulmonary pressure, thereby calming respiration.
According to research from 2020 Reliable Source, PDE5 inhibitors are effective for treating PE. However, they may enhance their efficacy with selective serotonin reuptake inhibitors (SSRIs).
Similar to other medications, PDE5 inhibitors provide enhanced ejaculatory control, increased confidence, and a delay in ejaculation.
All of the above ED treatments are available with a doctor’s prescription.
People taking nitrate drugs, such as Nitroglycerin, should not take PDE5 inhibitors due to the risk of a sudden drop in blood pressure.
Additionally, those wishing to use off-label ED medications, such as Viagra, must be aware of possible drug interactions. For instance, health professionals caution against combining the hypertension drug riociguat with ED medication.
Even though antidepressants are typically prescribed for treating depression and anxiety, several studies indicate that off-label use of two antidepressants may help cure PE by delaying ejaculations. SSRIs and tricyclic antidepressants (TCAs) include.
SSRI medications may be taken daily or as needed to treat PE, depending on their active constituents. These medications require between 1 and 5 hours to take effect when administered as needed. It takes two to three weeks for daily medications to take effect because a person typically begins with a low dose and progressively increases it.
Most antidepressant medications evaluated and approved by the FDATrusted Source are only available with a doctor’s prescription.
Typical antidepressant adverse effects include:
- stomach ache
- a case of diarrhea
- a lack of energy
- the process of perspiration
- The FDATrusted Source lists the following severe but uncommon adverse effects:
- epileptic seizures
- an erratic pulse
- Withdrawal indications
In rare instances, antidepressants may also cause erection difficulties.
The FDA Trusted Source advises individuals with narrow-angle glaucoma to use SSRIs and TCAs cautiously.
It also includes a list of medications that cannot be taken with antidepressants, including:
- Monoamine oxidase-inhibiting agents
- the drug thioridazine
- The drug pimozide
Tramadol is an analgesic that reduces the sensitivity of serotonin-producing receptors. It is available only with a doctor’s prescription. Tramadol for PE is an unapproved use.
Studies indicate that Tramadol can help individuals manage PE. It may function by inhibiting the serotonin transporter, with additional action by 5-HT(1A) receptors, which aid in ejaculatory function and inhibit erections.
A 2021 researchAccording to Reliable Source, administering the substance hours before sexual activity increased satisfaction and decreased PE.
Tramadol is a narcotic. These substances can contribute to dependence and abuse. To comprehend the risk of tramadol-induced opioid dependence, more research is required.
Individuals interested in taking Tramadol should know that the FDA has warned about the severe risks of combining this medication with benzodiazepines. It could be lethal.
Codeine is a variety of analgesic medications. The use of codeine for PE is unapproved.
In a 2017 study, one case was documented in which a person consuming codeine improved their ejaculatory control during sexual activity.
The individual in the preceding study depended on codeine, an opium derivative. Even though there were no liver or blood sugar abnormalities, the authors state that this individual had to undergo a 6-month withdrawal process.
People considering codeine for treating PE should consult a physician to determine the optimal course of action and minimize adverse effects.
Where to get PE pills
Doctors can advise patients on PE treatments that will not interact negatively with their current health conditions or medications. After receiving this information, individuals can purchase PE medication from the following direct-to-consumer health companies that ship products throughout the United States.
Customers must create profiles on the secure platforms of the companies and include their medical history and symptoms.
A healthcare professional will then review the individual’s application before responding to any inquiries, describing potential treatments, and authorizing medication.